Ketamine (also known as ket, K, special K, kitty, and others) is a classical dissociative substance of the arylcyclohexylamine class. It is the most well-known and widely-used among the dissociatives, a diverse group that includes phencyclidine (PCP), methoxetamine (MXE), dextromethorphan (DXM), and nitrous oxide. Recently, it has become the subject of significant clinical research due to the discovery that it can rapidly relieve treatment-resistant depression and suicidal ideation.
Cannabis as we know it, is the dried and cured flower of the cannabis plant notorious for it’s potent psychoactive effects when consumed. The principal psychoactive constituent of cannabis is tetrahydrocannabinol (THC), which is just one of hundreds of cannabinoids and other known compounds in the plant. Other notable potent and psychoactive compounds include such as cannabigerol (CBG), cannabidiol (CBD), cannabinol (CBN), and tetrahydrocannabivarin (THCV).
Despite being one of the most simply structured psychedelic compounds, DMT’s profound ability to create potent, yet short-lived, hallucinatory and visionary states makes it an appealing substance to many psychonauts.
Psilocybin mushrooms are a family of psychoactive fungi that contain psilocybin, a psychedelic substance of the tryptamine class. Psilocybin mushrooms occur on all continents and have been taxonomically classified into over 200 species, the most potent of which belong to the genus Psilocybe, the most common psychedelic mushroom and average user encounters. Other notably potent species include Panaeolus, Inocybes, Copelandia, and Gymnopilus.
Lysergic acid diethylamide (LSD) is a classical psychedelic, considered to be the most widely known, most researched, and culturally influential psychedelic substance of the modern age. This point may be argued by some, but its profound effect on the counterculture and direction of modern society, technology, and spirituality may never truly be comprehended.