Microdosing, in its current conceptual form, started to gain steam during the late 2010’s in Silicon Valley. The truth is, that it has likely been practiced for as many millennia as humans have been interacting with psychedelic substances. The act of microdosing involves periodically taking sub-perceptual doses of psychedelic drugs, like mushrooms or LSD, to experience reported benefits such as increased cognitive ability and creativity levels with less anxiety or experienced negative emotions. Those who have integrated microdosing into their life report long-term benefits that include: improved mood, better eating and sleeping habits, and less reliance on caffeine.
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Harm reduction, at its base layer, is a philosophy of public health with the intention of creating progressive lifestyle choices that could otherwise be prohibitive or damaging to ones psyche and body.
The central pillar of this philosophy stems from the recognition that humans will always engage in risky behaviors such as illicit drug use and casual sex. Ultimately harm reduction aims to reduce any potential harm that may come with these behaviors without denying, inhibiting, or criminalizing said behaviors. In turn this will only lead to more harm.
If you are like most of us who are microdosing you are doing it to help boost your creativity, presence, insight, and clearance of old patterns that no longer serve us. If you haven’t been microdosing, you’ve surely heard a bit about it by now.
The benefits seem almost too good to be true, given the minimal side effects and high efficacy when compared to their synthetic drug counterparts who strive to achieve the same beneficial outcomes. So how is it that microdosing psychedelic substances can produce such potent and lasting effects with such subtlety?
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Ketamine (also known as ket, K, special K, kitty, and others) is a classical dissociative substance of the arylcyclohexylamine class. It is the most well-known and widely-used among the dissociatives, a diverse group that includes phencyclidine (PCP), methoxetamine (MXE), dextromethorphan (DXM), and nitrous oxide. Recently, it has become the subject of significant clinical research due to the discovery that it can rapidly relieve treatment-resistant depression and suicidal ideation.
Cannabis as we know it, is the dried and cured flower of the cannabis plant notorious for it’s potent psychoactive effects when consumed. The principal psychoactive constituent of cannabis is tetrahydrocannabinol (THC), which is just one of hundreds of cannabinoids and other known compounds in the plant. Other notable potent and psychoactive compounds include such as cannabigerol (CBG), cannabidiol (CBD), cannabinol (CBN), and tetrahydrocannabivarin (THCV).
Despite being one of the most simply structured psychedelic compounds, DMT’s profound ability to create potent, yet short-lived, hallucinatory and visionary states makes it an appealing substance to many psychonauts.